Hi Mr Azooz, welcome to the forum..
Yes, as said by llamalord, you can..I have a X52 Pro, it is quite easy to use in the game..
Here's a tutorial about setting up controls in the game..
http://www.shipsim.com/ShipSimForum/index.php/topic,3472.0.html
ps: enter "throttle" in the search function, see how many posts there are about it..