All web pages have to be presented in HTML format.
If you mean "Do you write the plain HTML text, or do you use PHP, ASP, PERL etc to write the HTML code?", my answer is:
http://www.iso9000.co.uk - written using Notepad (I write the raw code)
Creators Forum - I wrote that in PERL, which then writes the HTML code "on the fly", depening on which buttons you have clicked.
But ultimately, no matter how the HTML code is produced, it has to be sent to your browser as HTML, or else it can't understand it.
<html>
<head>
<title>Page title here</title> etc.....