Hi Blackwellj, and welcome to the forums.
What exactly doesn't work with it, can you not map assingments to it at all? Or does it only partially work?
I have the previous model of that line, the x45 if I am not mistaken, and it works well. But I never have used a profile. I just mapped the desired assignments to the axis and buttons in the game itself. Does it work if you try that? Perhaps the Saitek software interferes.
Regards,
Fred